Difference in brain anatomy predict Alzheimer "
Difference predict Alzheimer brain anatomy - Note - Health - www.aztecanoticias.com.mx Saturday, April 16, 2011
How To Connect S/pdif
Chicago, USA .-
Differences in brain anatomy between older people maintain normalcy in their cognitive abilities can predict the risk of developing Alzheimer's in the next decade and quickly they will develop symptoms.
A study by the Medical Center Rush University in Chicago and the Massachusetts General Hospital, found that people with specific brain structures are thinner three times more likely to develop the disease than those with thicker than average.
To perform the analysis, the researchers turned to magnetic resonance imaging in two separate study groups, starting with the little attention it has received the monitoring process through the development of initial symptoms to final diagnosis. 
The neurologist Brad Dickerson, author of the study, said that "post mortem studies, we know that changes characteristic of Alzheimer's disease may be present in the brains of cognitively normal people. "
The neurologist Brad Dickerson, author of the study, said that "post mortem studies, we know that changes characteristic of Alzheimer's disease may be present in the brains of cognitively normal people. "" The results of the study change the signs of patients with dementia of Alzheimer's, providing the measurement of the areas where individuals not symptoms.
also determined that those who developed dementia showed declines subtle brain long before they had symptoms. "
The study, whose findings are published in the journal Neurology, shows that the brain measures to detect thinning of the main cortical areas could be important indicators to identify who may be at risk of developing Alzheimer's by up to 10 years in advance.
The study involved men and women aged 70 years, with similar levels of education, who filled out a complete clinical evaluation, including neuropsychological tests of memory.
In annual follow-up visits, each was re-evaluated to determine if they were cognitively normal or had mild cognitive impairment or probable Alzheimer's dementia.
The researchers analyzed data from 50 participants who were cognitively normal at baseline and who remained cognitively normal at the end of the study period and 15 who had developed disease over an average period of nine years.
In both study groups, the images revealed that the cerebral cortical areas associated with Alzheimer's disease in previous studies tend to be thinner in participants who went on to develop dementia.
Among those areas of the brain showed thinner, 55 percent developed dementia during the study period, compared with 20 percent of those with average thickness of cortical and none of the cortical thickness was above average.
Participants with thinner cortical areas also developed Alzheimer significantly faster than those with the average thickness.
These measures can help to detect the pattern of brain atrophy in Alzheimer's disease and is currently investigating various forms of use, such as dementia risk assessment in asymptomatic individuals.
Subscribe to:
Post Comments (Atom)
0 comments:
Post a Comment